The 2021-22 Southern Illinois Salukis went 16-15 (9-9 in the MVC) under head coach Bryan Mullins. Simple Rating System: 2.83.
| Date | Opponent | Result | Arena |
|---|---|---|---|
| 2021-11-09 | at Little Rock Trojans | L 66–69 | Jack Stephens Center |
| 2021-11-12 | vs Austin Peay Governors | W 73–55 | Banterra Center |
| 2021-11-19 | neutral Colorado Buffaloes | W 67–63 | Virgin Islands Sport & Fitness Center |
| 2021-11-21 | neutral Northeastern Huskies | L 47–59 | Virgin Islands Sport & Fitness Center |
| 2021-11-22 | neutral Creighton Bluejays | L 64–66 | Virgin Islands Sport & Fitness Center |
| 2021-11-26 | vs Alcorn State Braves | W 62–59 | Banterra Center |
| 2021-12-01 | at Evansville Purple Aces | W 54–52 | Ford Center |
| 2021-12-04 | vs Southern Miss Golden Eagles | W 66–41 | Banterra Center |
| 2021-12-11 | at Tulsa Golden Hurricane | L 65–69 | Donald W. Reynolds Center |
| 2021-12-15 | vs Southeast Missouri State Redhawks | W 80–55 | Banterra Center |
| 2021-12-18 | vs Maryville (MO) | W 75–55 | Banterra Center |
| 2021-12-22 | at San Francisco Dons | L 52–64 | War Memorial Gymnasium |
| 2021-12-28 | vs Grambling Tigers | W 75–64 | Banterra Center |
| 2022-01-08 | at Valparaiso Beacons | W 63–60 | Athletics-Recreation Center |
| 2022-01-12 | at Missouri State Bears | L 76–81 | JQH Arena |
| 2022-01-15 | vs Northern Iowa Panthers | L 68–69 | Banterra Center |
| 2022-01-17 | vs Drake Bulldogs | L 59–60 | Banterra Center |
| 2022-01-19 | vs Indiana State Sycamores | W 63–55 | Banterra Center |
| 2022-01-22 | at Bradley Braves | L 62–70 | Carver Arena |
| 2022-01-25 | at Loyola Chicago Ramblers | L 47–59 | Joseph J. Gentile Arena |
| 2022-01-27 | vs Loyola Chicago Ramblers | L 39–44 | Banterra Center |
| 2022-01-30 | vs Valparaiso Beacons | W 77–55 | Banterra Center |
| 2022-02-02 | vs Missouri State Bears | L 54–69 | Banterra Center |
| 2022-02-05 | at Illinois State Redbirds | W 75–69 | Redbird Arena |
| 2022-02-09 | at Northern Iowa Panthers | L 44–53 | McLeod Center |
| 2022-02-12 | vs Evansville Purple Aces | W 69–62 | Banterra Center |
| 2022-02-15 | vs Bradley Braves | W 65–57 | Banterra Center |
| 2022-02-19 | at Indiana State Sycamores | W 76–72 | Hulman Center |
| 2022-02-23 | vs Illinois State Redbirds | W 90–69 | Banterra Center |
| 2022-02-26 | at Drake Bulldogs | L 60–62 | Knapp Center |
| 2022-03-04 | neutral Drake Bulldogs | L 52–65 | Enterprise Center |
Southern Illinois Salukis program history · All Division I programs · Hoopsipedia home
| Rank | Team | Conference | All-Time Wins |
|---|
Top 100 by all-time D1 wins. Verified against the NCAA record book — and tiered so you can argue properly.
| # | COACH | RECORD | WIN % | SCHOOL(S) | YEARS | BEST SEASON / LEGACY |
|---|