The 2021-22 DePaul Blue Demons went 15-16 (6-14 in the Big East) under head coach Tony Stubblefield. Simple Rating System: 7.83.
| Date | Opponent | Result | Arena |
|---|---|---|---|
| 2021-11-10 | vs Coppin State Eagles | W 97–72 | Wintrust Arena |
| 2021-11-13 | vs Central Michigan Chippewas | W 99–66 | Wintrust Arena |
| 2021-11-18 | vs Rutgers Scarlet Knights | W 73–70 | Wintrust Arena |
| 2021-11-20 | vs Western Illinois Leathernecks | W 84–80 | Wintrust Arena |
| 2021-11-26 | vs Northern Kentucky Norse | W 77–68 | Wintrust Arena |
| 2021-11-28 | vs Eastern Michigan Eagles | W 101–63 | Wintrust Arena |
| 2021-12-04 | vs Loyola Chicago Ramblers | L 64–68 | Wintrust Arena |
| 2021-12-07 | vs Duquesne Dukes | W 87–67 | Wintrust Arena |
| 2021-12-10 | at Louisville Cardinals | W 62–55 | KFC Yum! Center |
| 2021-12-14 | at UIC Flames | W 72–66 | Credit Union 1 Arena |
| 2021-12-29 | at Butler Bulldogs | L 59–63 | Hinkle Fieldhouse |
| 2022-01-01 | vs Providence Friars | L 53–70 | Wintrust Arena |
| 2022-01-05 | at St. John's Red Storm | L 84–89 | Carnesecca Arena |
| 2022-01-08 | vs Villanova Wildcats | L 64–79 | Wintrust Arena |
| 2022-01-11 | at Marquette Golden Eagles | L 76–87 | Fiserv Forum |
| 2022-01-13 | vs Seton Hall Pirates | W 96–92 | Wintrust Arena |
| 2022-01-19 | vs Xavier Musketeers | L 67–68 | Wintrust Arena |
| 2022-01-22 | at Creighton Bluejays | L 47–60 | CenturyLink Center Omaha |
| 2022-01-25 | at Villanova Wildcats | L 43–67 | Finneran Pavilion |
| 2022-01-29 | vs UConn Huskies | L 50–57 | Wintrust Arena |
| 2022-02-05 | at Xavier Musketeers | W 69–65 | Cintas Center |
| 2022-02-09 | vs Georgetown Hoyas | W 82–74 | Wintrust Arena |
| 2022-02-12 | at Providence Friars | L 73–76 (OTOT) | Dunkin Donuts Center |
| 2022-02-15 | vs Butler Bulldogs | L 71–73 | Wintrust Arena |
| 2022-02-17 | vs Creighton Bluejays | L 59–71 | Wintrust Arena |
| 2022-02-19 | at Seton Hall Pirates | L 64–66 | Prudential Center |
| 2022-02-24 | at Georgetown Hoyas | W 68–65 | Capital One Arena |
| 2022-02-27 | vs St. John's Red Storm | W 99–94 | Wintrust Arena |
| 2022-03-02 | vs Marquette Golden Eagles | W 91–80 | Wintrust Arena |
| 2022-03-05 | at UConn Huskies | L 68–75 | Harry A. Gampel Pavilion |
| 2022-03-09 | neutral St. John's Red Storm | L 73–92 | Madison Square Garden (IV) |
DePaul Blue Demons program history · All Division I programs · Hoopsipedia home
| Rank | Team | Conference | All-Time Wins |
|---|
Top 100 by all-time D1 wins. Verified against the NCAA record book — and tiered so you can argue properly.
| # | COACH | RECORD | WIN % | SCHOOL(S) | YEARS | BEST SEASON / LEGACY |
|---|